Given the high number of patients at risk of VTE, and the relatively simple measures which can be employed to improve patient safety, a number of National and International Best Practice Guidelines have been developed through systematic literature reviews and expert consensus panels:
|Consensus statement / guideline
||Recommendations relating to IPC & AES
|NICE (UK) clinical guidelines (2010) 5
||Evidence based guideline for England and Wales based upon a systematic literature review.
No risk of bleeding
Can be used in combination with pharmacological methods for many groups of patients.
|Clinical practice guideline for the prevention of VTE in patients admitted to Australian hospitals (2009)
||Developed using internationally agreed methods for the development of evidence-based clinical practice guidelines.
||AES and IPC are recommended forms of prophylaxis used alone or in combination with pharmacological methods depending upon surgical procedure, medical condition and individual patient assessment.
|8th ACCP conference on anti-thrombotic therapy (2008)
||North American consensus statement featuring risk stratification, recommendations and expert consensus where insufficient evidence exists.
Mechanical methods of prophylaxis (AES & IPC) are recommended for patients at high risk of bleeding.
Recommended as an adjunct to anticoagulant-based thromboprophylaxis in higher risk patients.
|Australia and New Zealand Working Party on the Management and Prevention of Venous Thromboembolism. Best Practice Guidelines 4th Edition (2007)
||National guidelines developed by a working party to assist in the identification and treatment of patients at risk of developing DVT.
||IPC is more effective than AES in high-risk patients when combined with anticoagulants are contrainndicated.
|International Consensus Statement (2006)
||An international group recommending prophylactic measures in surgical, medical and obstetric patients.
Both IPC and AES reduce the risk of asymptomatic DVT.
Combinations of prophylactic methods are more effective than when used alone.